Table 1 Pairwise comparison of nonsynonymous (dN; above slash) and synonymous (dS; below slash) divergence between SARS-CoV-2, RaTG13, and Pangolin_2019 of different coding regions
From: The origin and underlying driving forces of the SARS-CoV-2 outbreak
Gene | Length (aa) | SARS-CoV-2 vs RaTG13 | SARS-CoV-2 vs Pangolin_2019 | RaTG13 vs Pangolin_2019 |
|---|---|---|---|---|
All | 9555 | 0.007/0.168 | 0.024/0.469 | 0.025/0.467 |
(0.042) | (0.051) | (0.054) | ||
orf1a | 4330 | 0.008/0.166 | 0.024/0.472 | 0.023/0.472 |
(0.048) | (0.051) | (0.049) | ||
orf1b | 2692 | 0.003/0.126 | 0.008/0.505 | 0.010/0.515 |
(0.024) | (0.016) | (0.019) | ||
spike | 1219 | 0.013/0.313 | 0.068/0.651 | 0.073/0.680 |
(0.040) | (0.104) | (0.107) | ||
RBD of spikeA | 219 | 0.055/0.511 | 0.023/0.710 | 0.058/0.863 |
(0.107) | (0.032) | (0.068) | ||
orf3 | 274 | 0.009/0.156 | 0.019/0.285 | 0.019/0.261 |
(0.060) | (0.066) | (0.072) | ||
envelope | 75 | 0/0.018 | 0/0.037 | 0/0.018 |
(0) | (0) | (0) | ||
matrix | 221 | 0.004/0.186 | 0.010/0.299 | 0.006/0.317 |
(0.021) | (0.033) | (0.019) | ||
orf6 | 60 | 0/0.099 | 0.014/0.220 | 0.014/0.345 |
(0) | (0.062) | (0.040) | ||
orf7 | 121 | 0.011/0.177 | 0.018/0.275 | 0.029/0.329 |
(0.061) | (0.066) | (0.088) | ||
orf8 | 121 | 0.032/0.303 | 0.025/0.362 | 0.017/0.391 |
(0.105) | (0.069) | (0.042) | ||
nucleocapsid | 415 | 0.005/0.124 | 0.011/0.145 | 0.010/0.125 |
(0.042) | (0.076) | (0.080) |