Fig. 2From: The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosisRegulation of PD-L1 N-linked glycosylation and its effective therapeutics. Multiple regulatory mechanisms with molecular or pharmacological regulators are involved in PD-L1 N-linked glycosylation, which is essential to maintain its protein stability. Red rounded rectangles represent molecules that upregulate PD-L1. Green ellipses represent molecules that downregulate PD-L1. Orange circles represent protein phosphorylation (P). ER, endoplasmic reticulum. Additional details can be found in the main text. Not drawn to scaleBack to article page