Fig. 6

The survival of RS218 strains with and without cjrABC-senB in the bloodstream of CVF-treated mice and PBS-treated mice. Equal numbers of Cjr⁻-RS218 and Cjr⁺-∆lacZ-RS218 were co-inoculated into mice pretreated with CVF or PBS. At 14 h post-inoculation, the competitive index (CI) of Cjr⁻-RS218 v.s. Cjr⁺-∆lacZ-RS218 in the animals were determined. The CI was calculated as follows: CI = (bacterial counts of Cjr⁻-RS218/bacterial counts of Cjr⁺-∆lacZ-RS218)/ (inoculum counts of Cjr⁻-RS218/inoculum counts of Cjr⁺-∆lacZ-RS218). The horizontal bars represent the median values. *, P value < 0.05; ***, P value < 0.001