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Table 4 Comparison of clinical characters of non-vaccine serotypes and vaccine serotypes related definite pneumococcal pneumonia

From: The potential role of pneumococcal conjugate vaccine in reducing acute respiratory inflammation in community-acquired pneumococcal pneumonia

 

Coverage serotype

p-value

Noc

Yesd

N = 21

N = 37

Processing of pneumonia severity

 Pleural fluid aspiration

7 (33.33)

19 (51.35)

0.185a

 Chest catheter use

12 (57.14)

31 (83.78)

0.026a

 VATS

9 (42.86)

29 (78.38)

0.006a

 ICU admission

12 (57.14)

30 (81.08)

0.050a

 Days in ICU

6.9 ± 4.1

8.6 ± 11.9

0.635b

 O2 use

14 (66.67)

30 (81.08)

0.218a

 O2 use day >=7 days

8 (38.10)

16 (43.24)

0.702a

 Admission days >= 14 days

12 (57.14)

29 (78.38)

0.088a

 One of the above

16 (76.19)

37 (91.38)

0.004a

 Two of the above

14 (66.67)

36 (97.30)

0.002a

 Three of the above

14 (66.67)

34 (91.89)

0.027a

Blood tests

 Lowest Hb (g/ dl)

10.0 ± 1.8

9.2 ± 0.9

0.049b

 Highest WBC (x k/ cumm)

19.6 ± 9.2

24.1 ± 9.3

0.080b

 Highest Bandemia (%)

6.9 ± 9.1

11.6 ± 17.0

0.198b

 Highest Neutrophilis (x k/ cumm)

39.1 ± 31.6

55.6 ± 32.4

0.069b

 Highest Lymphocytes (x k/ cumm)

11.9 ± 14.1

18.4 ± 16.5

0.132b

 Highest Eosinophils (x k/ cumm)

0.9 ± 1.8

2.2 ± 2.4

0.038b

 Highest Platelets (x k/ cumm)

577.8 ± 228.9

663.4 ± 249.0

0.201b

 Highest CRP (mg/ dl)

23.7 ± 10.6

29.5 ± 9.8

0.038b

  1. Numbers in bold indicate statistical significance (p<0.05)
  2. Data are shown as N (%) for categorical variable and mean ± standard deviation for continuous variable; VATS, video-assisted thoracoscopic surgery; ICU, intensive care unit
  3. a Chi-square test
  4. b Student's t-test
  5. c all of the non-vaccine coverage serotypes are unknown serotypes
  6. d vaccine coverage serotype including 7 with serotype 3, one case with serotype 6, 27 with serotype 19A, 2 with serotype 19F