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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank

Fig. 2

Characterization of variants generated during reprogramming in 10 normal iPSC lines. a A flowchart describing the filtering strategy used to obtain SNVs, structural variants and somatic variants specific to reprogrammed cell line using GATK HaplotypeCaller, DELLY2 and MuTect2. b-d The number of single nucleotide variants (SNV), deletions (DEL), insertion (INS) and multi-nucleotide variations (MNV) of iPSC-specific qualified variants among iPSCs identified by b GATK HaplotypeCaller, c DELLY2, and d MuTect2. e-g Distribution of variant categories of iPSC-specific qualified variants among iPSCs identified by e GATK HaplotypeCaller, f DELLY2, and g MuTect2. Data in e, f, and g are represented as mean ± SEM

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