TY - JOUR AU - Ju, Wen AU - Lu, Wenyi AU - Ding, Lan AU - Bao, Yurong AU - Hong, Fei AU - Chen, Yuting AU - Gao, Hui AU - Xu, Xiaoqi AU - Wang, Guozhang AU - Wang, Weiwei AU - Zhang, Xi AU - Fu, Chunling AU - Qi, Kunming AU - Li, Zhenyu AU - Xu, Kailin AU - Qiao, Jianlin AU - Zeng, Lingyu PY - 2020 DA - 2020/09/01 TI - PEDF promotes the repair of bone marrow endothelial cell injury and accelerates hematopoietic reconstruction after bone marrow transplantation JO - Journal of Biomedical Science SP - 91 VL - 27 IS - 1 AB - Preconditioning before bone marrow transplantation such as irradiation causes vascular endothelial cells damage and promoting the repair of damaged endothelial cells is beneficial for hematopoietic reconstitution. Pigment epithelium-derived factor (PEDF) regulates vascular permeability. However, PEDF’s role in the repair of damaged endothelial cells during preconditioning remains unclear. The purpose of our study is to investigate PEDF’s effect on preconditioning-induced damage of endothelial cells and hematopoietic reconstitution. SN - 1423-0127 UR - https://doi.org/10.1186/s12929-020-00685-4 DO - 10.1186/s12929-020-00685-4 ID - Ju2020 ER -