Fig. 1From: PEDF promotes the repair of bone marrow endothelial cell injury and accelerates hematopoietic reconstruction after bone marrow transplantationIn vitro analysis of the effect of injured EC on HSC expansion, cell cycle, apoptosis and differentiation in a co-culture system. a Representative Microscopic observation of HSC expansion after cocultured with normal or damaged endothelial cells for 7 days; b Flow cytometry analysis of the proportion and number of HSCs after co-culture with normal endothelial cells or damaged endothelial cells. c HSC cell cycle analysis by flow cytometry; d HSC apoptosis analysis; e Colony-forming capacity of HSCs after co-culture; f Flow cytometry analysis of the proportion of erythrocytes, granulocytosis and thrombocytosis (n = 3–4, * P < 0.05, ** p < 0.01, *** p < 0.0001)Back to article page