Fig. 4

PEDF protects endothelial injury from the function-inhibiting effect of hematopoietic stem cells. a Representative microscopic observation of HSC expansion after cocultured with normal or damaged endothelial cells for 7 days with or without PEDF (× 100) and total number of cultured HSC analysis. b Flow cytometry detection of HSC proliferation. c Flow cytometry analysis of the proportion of erythrocytes, myeloid cells and megakaryocytes (n = 3, * P < 0.05, ** p < 0.01, *** p < 0.001)