Fig. 6

Effect of hG-CSF gene therapy on the Caspase 12 and pAKT. a, b Western blot analysis of cleaved caspase 12 (cleaved casp 12) a 4- and b 7-days post-BCAO. c, d similarly western blot analysis of pAKT in the frontal and middle brain sections of sham, AAV-CMV-GFP and AAV-CMV-hG-CSF treated mice at c 4- and d 7- days post-BCAO. Statistical analysis was performed by One Way ANOVA, with Tukey as post hoc test and expressed as means ± S.E.M; *p < 0.05/**p < 0.01/***p < 0.001 versus Sham group while ^#p < 0.05/##p < 0.01/^###p < 0.001 versus AAV-CMV-GFP- treated group. (n = 7 animals/group)