Journal of Biomedical Science

Table 2 The most up and down-regulated mRNA expression profile of ESCC cell lines by oligonucleotide microarray analysis

From: MicroRNA-146a suppresses tumor malignancy via targeting vimentin in esophageal squamous cell carcinoma cells with lower fibronectin membrane assembly

Gene symbol	Regulation	log FC^a
NDRG1	Up	4.07
SLC2A3	Up	3.70
SMG1	Up	2.54
IL1A	Up	2.51
LIMCH1	Up	2.51
TMEM123	Up	2.33
DDX21	Up	2.27
HERC5	Up	2.25
NUDT21	Up	2.25
PLOD2	Up	2.25
BIRC3	Up	2.23
IFIT2	Up	2.21
SMC3	Up	2.13
FAM60A	Up	2.08
UBE2V2	Up	2.07
ITGAV	Up	2.05
FAM18B	Up	2.04
CETN3	Up	2.04
ITGB1	Up	2.01
NMD3	Up	1.99
HSPA1A	Down	− 1.94
ATF5	Down	− 1.77
PTHLH	Down	− 1.66
HSPA1B	Down	− 1.62
C16ORF53	Down	− 1.61
GRWD1	Down	− 1.59
MPDU1	Down	− 1.56
TRPM2	Down	− 1.56
DDX54	Down	− 1.55
PTHLH	Down	− 1.51
S100A2	Down	− 1.47
LFNG	Down	− 1.47
MEPCE	Down	− 1.44
DDX39	Down	− 1.43
AVEN	Down	− 1.41
MPDU1	Down	− 1.40
POLR2L	Down	− 1.39
LYPD1	Down	− 1.38
LANCL2	Down	− 1.38
VIM^b	Down	− 0.41

1—CE81^FN+ cells were transiently transfected with N.C. or mimic-miR-146a. 2—CE81^FN+ + CON and CE81^FN+ + 146a stable cell lines. The cells from 1 and 2 were under the microarray analyzed by Illumina gene expression system. The Illumina chip contains 47,231 probes and over 31,000 genes. The data shows the differential gene expression profile of 1 and 2
^aRepresents as log of fold change of 2
^bVimentin (VIM) expression was down-regulated in this microarray

Back to article page

ISSN: 1423-0127

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com