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Table 2 The most up and down-regulated mRNA expression profile of ESCC cell lines by oligonucleotide microarray analysis

From: MicroRNA-146a suppresses tumor malignancy via targeting vimentin in esophageal squamous cell carcinoma cells with lower fibronectin membrane assembly

Gene symbol Regulation log FCa
NDRG1 Up 4.07
SLC2A3 Up 3.70
SMG1 Up 2.54
IL1A Up 2.51
LIMCH1 Up 2.51
TMEM123 Up 2.33
DDX21 Up 2.27
HERC5 Up 2.25
NUDT21 Up 2.25
PLOD2 Up 2.25
BIRC3 Up 2.23
IFIT2 Up 2.21
SMC3 Up 2.13
FAM60A Up 2.08
UBE2V2 Up 2.07
ITGAV Up 2.05
FAM18B Up 2.04
CETN3 Up 2.04
ITGB1 Up 2.01
NMD3 Up 1.99
HSPA1A Down − 1.94
ATF5 Down − 1.77
PTHLH Down − 1.66
HSPA1B Down − 1.62
C16ORF53 Down − 1.61
GRWD1 Down − 1.59
MPDU1 Down − 1.56
TRPM2 Down − 1.56
DDX54 Down − 1.55
PTHLH Down − 1.51
S100A2 Down − 1.47
LFNG Down − 1.47
MEPCE Down − 1.44
DDX39 Down − 1.43
AVEN Down − 1.41
MPDU1 Down − 1.40
POLR2L Down − 1.39
LYPD1 Down − 1.38
LANCL2 Down − 1.38
VIMb Down − 0.41
  1. 1—CE81FN+ cells were transiently transfected with N.C. or mimic-miR-146a. 2—CE81FN+ + CON and CE81FN+ + 146a stable cell lines. The cells from 1 and 2 were under the microarray analyzed by Illumina gene expression system. The Illumina chip contains 47,231 probes and over 31,000 genes. The data shows the differential gene expression profile of 1 and 2
  2. aRepresents as log of fold change of 2
  3. bVimentin (VIM) expression was down-regulated in this microarray
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Journal of Biomedical Science

ISSN: 1423-0127