| HONE-1 (µM) | TW01 (µM) |
---|
Control | 10.5 ± 0.5 | 122.2 ± 8.2 |
O6BG | 5.2 ± 0.4 | 61.5 ± 10.8 |
- IC50 values of olaparib were determined using a cell viability assay. Cells in the exponential phase were first treated with O6BG (120 µM) for 8 h. After medium removal and cell washing, serial concentrations of olaparib were added for three generation times. Values are presented as means ± SDs of at least three independent experiments