|
HONE-1 (µM)
|
TW01 (µM)
|
---|
Control
|
10.5 ± 0.5
|
122.2 ± 8.2
|
O6BG
|
5.2 ± 0.4
|
61.5 ± 10.8
|
- IC50 values of olaparib were determined using a cell viability assay. Cells in the exponential phase were first treated with O6BG (120 µM) for 8 h. After medium removal and cell washing, serial concentrations of olaparib were added for three generation times. Values are presented as means ± SDs of at least three independent experiments