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Table 4 List of enriched Kyoto encyclopedia of genes and genomes (KEGG) pathways in the differentially expressed proteins (DEPs) of acetate-grown C. glabrata

From: Transcriptomic and proteomic profiling revealed reprogramming of carbon metabolism in acetate-grown human pathogen Candida glabrata

Pathway Count Frequency (%) EASE score
Up-regulated
 Metabolic pathways 60 35.7 1.50E−12
 Biosynthesis of secondary metabolites 34 20.2 1.00E−08
 Carbon metabolism 19 11.3 1.50E−07
 Citrate cycle (TCA cycle) 11 6.5 2.40E−07
 Biosynthesis of antibiotics 26 15.5 6.50E−07
 Oxidative phosphorylation 14 8.3 5.30E−06
 Pyruvate metabolism 9 5.4 9.60E−05
 Biosynthesis of amino acids 16 9.5 1.30E−04
 2-Oxocarboxylic acid metabolism 8 4.8 7.80E−04
 Glyoxylate and dicarboxylate metabolism 6 3.6 2.00E−03
 Glycolysis/gluconeogenesis 7 4.2 1.80E−02
 Pentose and glucuronate interconversions 3 1.8 2.80E−02
 Arginine biosynthesis 4 2.4 3.40E−02
 Alanine, aspartate and glutamate metabolism 4 2.4 9.40E−02
Down-regulated
 Metabolic pathways 14 29.8 6.00E−03
 Biosynthesis of antibiotics 7 14.9 1.90E−02
 Cysteine and methionine metabolism 3 6.4 5.30E−02
 Biosynthesis of secondary metabolites 7 14.9 7.20E−02