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Table 4 List of enriched Kyoto encyclopedia of genes and genomes (KEGG) pathways in the differentially expressed proteins (DEPs) of acetate-grown C. glabrata

From: Transcriptomic and proteomic profiling revealed reprogramming of carbon metabolism in acetate-grown human pathogen Candida glabrata

Pathway

Count

Frequency (%)

EASE score

Up-regulated

 Metabolic pathways

60

35.7

1.50E−12

 Biosynthesis of secondary metabolites

34

20.2

1.00E−08

 Carbon metabolism

19

11.3

1.50E−07

 Citrate cycle (TCA cycle)

11

6.5

2.40E−07

 Biosynthesis of antibiotics

26

15.5

6.50E−07

 Oxidative phosphorylation

14

8.3

5.30E−06

 Pyruvate metabolism

9

5.4

9.60E−05

 Biosynthesis of amino acids

16

9.5

1.30E−04

 2-Oxocarboxylic acid metabolism

8

4.8

7.80E−04

 Glyoxylate and dicarboxylate metabolism

6

3.6

2.00E−03

 Glycolysis/gluconeogenesis

7

4.2

1.80E−02

 Pentose and glucuronate interconversions

3

1.8

2.80E−02

 Arginine biosynthesis

4

2.4

3.40E−02

 Alanine, aspartate and glutamate metabolism

4

2.4

9.40E−02

Down-regulated

 Metabolic pathways

14

29.8

6.00E−03

 Biosynthesis of antibiotics

7

14.9

1.90E−02

 Cysteine and methionine metabolism

3

6.4

5.30E−02

 Biosynthesis of secondary metabolites

7

14.9

7.20E−02