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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Advances in sepsis diagnosis and management: a paradigm shift towards nanotechnology

Fig. 2

Schematic presentation of general protocol and principle of different electrochemical sensors. a Potentiometric antibody immobilized ZnO nanotubes-based biosensor for the detection of CRP; the calibration curve of bare ZnO nanotubes for CRP-antigen (b) and antibody immobilized ZnO nanotubes for CRP (c) [64]. d Different steps involved in the preparation of the dual electrochemical immunosensor for multiplexed determination of IL-1b and TNF-α cytokines. Calibration plots for IL-1b (e) and TNF-α (f) obtained with the dual poly-HRP-Strept-Biotin-anti-IL-IL1b-anti-IL-Phe-DWCNTs/SPCE and poly-HRP-Strept-Biotin-anti-TNF-TNF-α-anti-TNF-Phe-DWCNTs/SPCE immunosensor [68]

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