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Table 1 Effect of columbianadin (CBN) and aspirin on mortality of acute pulmonary thrombosis caused by intravenous injection of ADP in experimental mice

From: Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin αIIbβ3 inside-out but not outside-in signals

 

Total number

Number of deaths

Mortality (%)

ADP (0.7 mg/g)

  + solvent control (0.1% DMSO)

8

8

100

  + CBN (5 mg/kg)

8

4

50

  + CBN (10 mg/kg)

8

0

0

  + aspirin (20 mg/kg)

8

2

25