- Calculation of Pearson’s correlation coefficient indicates the relationship between the gene expression of markers for inflammation, injury and fibrosis along a time course between 6 h and 10 d. The time courses of the tubular injury score and neutrophil influx between 0 h and 3 d was calculated separately. While Tnf-α and Il-6 revealed a strong negative relation, Kim-1 and Clusterin, Tnf-α and Col1a1, Tgf-ß1 and Col1a1, Tgf-ß1 and Laminin, and Col1a1 and Laminin showed a strong positive correlation. The correlation of the course of the tubular injury score and the neutrophil influx was strong positiv. A correlation coefficient between +/− 0.8 and +/− 1 was defined as „strong positive/negative correlation”
- Col1a1 Collagen, type I, α 1, Ccl-2 chemokine (C-C motif) ligand 2, Il-6 Interleukin 6, Kim-1 Kidney injury molecule 1, Ngal Neutrophil gelatinase-associated lipocalin, Tgf-β1 Transforming growth factor β 1, Tnf-α Tumor necrosis factor-α, TIS Tubular injury score