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Table 3 Correlation between gene expression markers for inflammation, injury and fibrosis and between the tubular injury score and the neutrophil influx

From: “Point of no return” in unilateral renal ischemia reperfusion injury in mice

  1. Calculation of Pearson’s correlation coefficient indicates the relationship between the gene expression of markers for inflammation, injury and fibrosis along a time course between 6 h and 10 d. The time courses of the tubular injury score and neutrophil influx between 0 h and 3 d was calculated separately. While Tnf-α and Il-6 revealed a strong negative relation, Kim-1 and Clusterin, Tnf-α and Col1a1, Tgf-ß1 and Col1a1, Tgf-ß1 and Laminin, and Col1a1 and Laminin showed a strong positive correlation. The correlation of the course of the tubular injury score and the neutrophil influx was strong positiv. A correlation coefficient between +/− 0.8 and +/− 1 was defined as „strong positive/negative correlation”
  2. Col1a1 Collagen, type I, α 1, Ccl-2 chemokine (C-C motif) ligand 2, Il-6 Interleukin 6, Kim-1 Kidney injury molecule 1, Ngal Neutrophil gelatinase-associated lipocalin, Tgf-β1 Transforming growth factor β 1, Tnf-α Tumor necrosis factor-α, TIS Tubular injury score
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Journal of Biomedical Science

ISSN: 1423-0127