Antivirals blocking entry of enteroviruses and therapeutic potential

Table 3 Antiviral peptides against enteroviruses

Peptide	Sequence	Potency (EC₅₀ or IC₅₀)	EV inhibited	Refs
SP40	Ac-QMRRKVELFTYMRFD-NH₂	6–9.3 µM	EV-A71, CV-A16, PV1	[88]
SP45	Ac-AEFTFVACTPTGEVV-NH₂	N/A	EV-A71	[88]
SP55	Ac-PESRESLAW-NH₂	N/A	EV-A71	[88]
SP81	Ac-SKSKYPLVVRIYMRMKHVRAW-NH₂	N/A	EV-A71	[88]
LVLQTM	LVLQTM	nM–µM	EV-A71, Echo-6, RV-2	[90, 91]
Tripeptide VAD	VAD	µM	RV-2	[92]
Tetrapeptide AAPV	AAPV	µM	PV-1, CV-A21, RV-2	[93]

ISSN: 1423-0127