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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Gut microbiota-mediated lysophosphatidylcholine generation promotes colitis in intestinal epithelium-specific Fut2 deficiency

Fig. 5

Altered gut microbiota and metabolism in Fut2△IEC mice. a The alpha diversity (Chao1 index) in four groups. b The PCoA plots of unweighted UniFrac distances of beta diversity. c, d Relative abundance of microbial family and genus in different groups. e Relative abundance of microbiota at the genus level. f Increased metabolite of Fut2△IEC versus WT mice when exposed to DSS. g Volcano Plot of differential metabolites in WT mice and Fut2△IEC mice in DSS group (Fut2△IEC mice versus WT mice). h The level of fecal LPC in four groups. i The level of PLA in four groups. Data were shown as mean ± SEM (n = 5 per group). The data come from three independent experiments. In all panels: *p < 0.05, **p < 0.01, ***p < 0.001. (LPC Lysophosphatidylcholine, PLA Phospholipase A)

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