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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Rheumatoid cachexia: the underappreciated role of myoblast, macrophage and fibroblast interplay in the skeletal muscle niche

Fig. 4

Summary of the interaction between macrophages, fibroblasts and FAPs in the development of tissue fibrosis. TNF-α  tumor necrosis factor-alpha, IL-6  interleukin-6, TGFβ  transforming growth factor-beta, FAPs  fibro-adipogenic progenitor cells, TIMPs  tissue inhibitor of metalloproteinase, MMPs  metalloproteinases

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