Fig. 4From: Rheumatoid cachexia: the underappreciated role of myoblast, macrophage and fibroblast interplay in the skeletal muscle nicheSummary of the interaction between macrophages, fibroblasts and FAPs in the development of tissue fibrosis. TNF-α  tumor necrosis factor-alpha, IL-6  interleukin-6, TGFβ  transforming growth factor-beta, FAPs  fibro-adipogenic progenitor cells, TIMPs  tissue inhibitor of metalloproteinase, MMPs  metalloproteinasesBack to article page