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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity

Fig. 1

Biochemical analysis, fat deposits and PVAT of obese mice after pioglitazone treatment. a Plasma glucose, b aortic pulse wave velocity (PWV), c heart rate, d mean BP, e body weight, the ratio of f gonadal fat weight/body weight, g inguinal fat weight/body weight, and h gonadal/inguinal fat weight were measured in 3-month-old male control, ob/ob, and pioglitazone-treated ob/ob (ob/ob + Piog) mice. i PVAT was visualized in 3-month-old male mice and j its weight was normalized to body weight. Numbers inside the bar = n in each group. k Histological examination of aorta and PVAT. l Expression of brown adipocyte markers in the PVAT (n = 3, 5, and 6 for control, ob/ob, and ob/ob + Piog groups respectively). All data are resulted from 3-month-old male mice. ob/ob mice were treated with pioglitazone for 1 month starting at 2 months of age. *P < 0.05, **P < 0.01, and ***P < 0.001

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