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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity

Fig. 2

Expression of inflammatory mediators and reactive oxygen species-related enzymes in the aorta and PVAT. Expression of genes for chemokines, macrophage markers, and cytokines in the a aorta (n = 7, 5, and 6 for control, ob/ob, and ob/ob + Piog groups respectively) and b PVAT (n = 3, 5, and 6 for control, ob/ob, and ob/ob + Piog groups respectively). Expression of genes for ROS-scavenging enzymes and components of NADPH oxidase in the c aorta (n = 7, 5, and 6 for control, ob/ob, and ob/ob + Piog groups respectively) and d PVAT (n = 3, 5, and 6 for control, ob/ob, and ob/ob + Piog groups respectively). mRNA amount is expressed relative to the average expression in control mice. All data are resulted from 3-month-old male mice. ob/ob mice were treated with pioglitazone for 1 month starting at 2 months of age. *P < 0.05, **P < 0.01, and ***P < 0.001

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