Fig. 4

TMED9 expression correlates with overall and disease-free survival in patients with hepatocellular carcinoma (HCC) after surgical resection. a Tissue microarray of HCC was immunohistochemically analyzed for TMED9 and showed different intensity scores for TMED9 expression. b TMED9 expression scores were significantly higher in tumor than non-tumor tissues. Statistical significance was analyzed by a paired t test (p < 0.0001). c, d Kaplan–Meier plot of overall c and disease-free d survival of 182 patients with HCC stratified by TMED9 expression levels. A log-rank test was used to show differences between groups