Skip to main content
Fig. 2 | Journal of Biomedical Science

Fig. 2

From: A novel pseudovirus‐based mouse model of SARS-CoV-2 infection to test COVID-19 interventions

Fig. 2

Efficacy of blocking SARS-CoV-2 PsV infection using soluble RBD in vitro. Ability of RBD to block WT (a), 19del (b), or 19del + D614G (c) pseudovirus infection. Following preincubation with RBD protein, hACE2 expressing 293TT cells were infected with WT, 19del, or 19del + D614G SARS-CoV-2 pseudoviruses (quantified as 25ng of HIV Gag p24 protein). 72 h later, cells were harvested and RLU was determined as a readout for infection. Data expressed as mean ± SEM. Student’s t test used to analyze differences between groups. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

Back to article page