Fig. 2
From: The m6A epitranscriptome on neural development and degeneration
The roles of m6A in the developing central nervous system. m6A RNA modifications play important roles in regulating neural development, including embryonic neurogenesis, OPC differentiation, myelination, adult NSC differentiation, synaptic formation and neuronal maturation. The panels summarize the physiological functions of m6A during neural development, as revealed by loss-of-function studies on m6A-associated proteins. NPC, neural progenitor cell; RGC, radial glial cell; IPC, intermediate progenitor cell; NSC, neural stem cell; OPC, oligodendrocyte progenitor cell; CBP, CREB binding protein; H3K27ac, histone H3 lysine 27 acetylation; H3K27me3, histone H3 lysine 27 trimethylation