From: New therapeutic approaches of mesenchymal stem cells-derived exosomes
NCT number | Study title | Study start | Condition | Intervention | Phase | Status |
---|---|---|---|---|---|---|
NCT04602104 | A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS | October 2020 | Acute Respiratory Distress Syndrome | Allogenic human MSC-Exos | Phase 1 Phase 2 | Not yet recruiting |
NCT04602442 | Safety and Efficiency of Method of Exosome Inhalation in COVID-19 Associated Pneumonia (COVID-19EXO2) | October 1, 2020 | Covid19; SARS-CoV-2 PNEUMONIA | MSC-Exos | Phase 2 | Enrolling by invitation |
NCT04173650 | MSC EVs in Dystrophic Epidermolysis Bullosa | September 2020 | Dystrophic Epidermolysis Bullosa | AGLE 102 | Phase 1 Phase 2 | Not yet recruiting |
NCT04356300 | Exosome of Mesenchymal Stem Cells for Multiple Organ Dysfuntion Syndrome After Surgical Repaire of Acute Type A Aortic Dissection | September 1, 2020 | Multiple Organ Failure | UC MSC-Exos | Not Applicable | Not yet recruiting |
NCT04491240 | Evaluation of Safety and Efficiency of Method of Exosome Inhalation in SARS-CoV-2 Associated Pneumonia | July 20, 2020 | Covid19; SARS-CoV-2 PNEUMONIA | MSC-Exos | Phase 1 Phase 2 | Completed has results |
NCT04544215 | A Clinical Study of Mesenchymal Progenitor Cell Exosomes Nebulizer for the Treatment of Pulmonary Infection | July 1, 2020 | Drug-resistant | Human AD MS progenitor cell-Exos | Phase 1 Phase 2 | Recruiting |
NCT04388982 | the Safety and the Efficacy Evaluation of Allogenic Adipose MSC-Exos in Patients With Alzheimer's Disease | July 1, 2020 | Alzheimer´s Disease | allogenic AD MSC-Exos | Phase 1 Phase 2 | Recruiting |
NCT03608631 | iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation | March 2020 | Pancreatic cancer with KrasG12D mutation; Metastatic Pancreatic Adenocarcinoma; Pancreatic Ductal Adenocarcinoma; Stage IV Pancreatic Cancer AJCC v8 | MSC-Exos with KRAS G12D siRNA | Phase 1 | Not yet recruiting |
NCT04313647 | A Tolerance Clinical Study on Aerosol Inhalation of Mesenchymal Stem Cells Exosomes In Healthy Volunteers | March 16, 2020 | Healthy | Allogenic AD MSC-Exos | Phase 1 | Recruiting |
NCT04213248 | Effect of UMSCs Derived Exosomes on Dry Eye in Patients With cGVHD | February 18, 2020 | Dry Eye | UC MSC-Exos | Phase 1 Phase 2 | Recruiting |
NCT04276987 | A Pilot Clinical Study on Inhalation of Mesenchymal Stem Cells Exosomes Treating Severe Novel Coronavirus Pneumonia | February 15, 2020 | Coronavirus | Allogenic AD MSC-Exos | Phase 1 | Completed |
NCT03384433 | Allogenic Mesenchymal Stem Cell Derived Exosome in Patients With Acute Ischemic Stroke | April 17, 2019 | Cerebrovascular Disorders | Allogenic MSC-Exos enriched by miR-124 | Phase 1 Phase 2 | Recruiting |
NCT03437759 | MSC-Exos Promote Healing of MHs | March 1, 2017 | Macular Holes | MSC-Exos | Early Phase 1 | Recruiting |
NCT03562715 | microRNAs Role in Pre-eclampsia Diagnosis | November 28, 2016 | Pre-eclampsia | Â | Â | Completed |
NCT02138331 | Effect of Microvesicles and Exosomes Therapy on β-cell Mass in Type I Diabetes Mellitus (T1DM) | April 2014 | Diabetes Mellitus Type 1 | UC blood MSC-Exos | Phase 2 Phase 3 | Unknown |