Skip to main content
Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

Fig. 3

Confirmation of the effects of TGF-β2 on ATX protein expression in hTM cells by immunocytochemistry. Immunocytochemistry of ATX in TGF-β2-stimulated hTM cells. Left panels present cells that were stained with DAPI (4’,6-diamidino-2-phenylindole). Middle panels present cells stained for ATX. Right panels present merged images. Characteristic ATX protein expression in vesicles was evident after treatment with TGF-β2 at concentrations of 0.01 and 0.1 ng/ml, while ATX protein expression was downregulated after treatment with TGF-β2 at the concentration of 1 ng/ml. These effects were significantly suppressed by treatment with the TGF-β inhibitor SB431542. Bar, 200 µm

Back to article page