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Table 3 miRNA regulation in the glycan precursor synthesis

From: Systems glycobiology for discovering drug targets, biomarkers, and rational designs for glyco-immunotherapy

microRNA Gene target Function role of gene target in glycosylation Regulatory effect in tumor References
miR-1291 SLC2A1 Glucose transporter Tumor Suppressive [99]
miR-30c-2-3p SLC2A1 Glucose transporter Unknown [100]
miR‐195‐5p SLC2A3 Glucose transporter Tumor Suppressive [101]
miR-106a SLC2A3 Glucose transporter Tumor Suppressive [102]
miR-129-5p SLC2A3 Glucose transporter Tumor Suppressive [103]
miR-223 SLC2A4 Glucose transporter Unknown [104]
miR-133 SLC2A4 Glucose transporter Unknown [105]
miR-22 SLC35B2 Nucleotide Sugar Transport Tumor Suppressive [106]
miR-1764,
miR-1700
SLC35B4 Nucleotide Sugar Transport Unknown [107]
miR-369-3p SLC35F5 Nucleotide Sugar Transport Tumor Suppressive [108]
miR-32 SLC45A3 Glucose transporter Unknown [109]
miR-139-5p HK1 Nucleotide Sugar Metabolism Tumor Suppressive [37]
miR-143 HK2 Nucleotide Sugar Metabolism Unknown [38]
miR-34a GPI Nucleotide Sugar Metabolism Unknown [40]
miR‑224‑5p UAP1 Nucleotide Sugar Metabolism Tumor Suppressive [41]
miR‑451a PMM2 Nucleotide Sugar Metabolism Tumor Suppressive [110]
miR‑125a-5p, miR-125b TSTA3 Nucleotide Sugar Metabolism Tumor Suppressive [111]
miR-29a-3p,
miR-29b-3p
CMAHP Nucleotide Sugar Metabolism Tumor Suppressive [112]