Fig. 8From: Chandipura virus dysregulates the expression of hsa-miR-21-5p to activate NF-κB in human microglial cells The CHPV mediated regulation of inflammatory responses by perturbation of hsa-miR-21-5p in human microglial cells. CHPV infection in human microglial cells increases the expression of hsa-miR-21-5p. The microRNA targets and supresses the expression of PTEN which in turns promotes phosphorylation and activation of AKT and NF-κBp65 in human microglial cellsBack to article page