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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: RETRACTED ARTICLE: Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis

Fig. 5

Silenced NEAT1 inhibits ovarian granulosa cell apoptosis in PCOS rats. A TUNEL assay was used to detect the apoptosis of ovarian granulosa cells in PCOS rats after down-regulation of NEAT1 (Scale bar = 50 μm); B Apoptotic index of ovarian granulosa cells in PCOS rats after down-regulation of NEAT1; C Protein bands of Cleaved caspase-3, caspase-3, Bax and Bcl-2 in PCOS rats after down-regulation of NEAT1. D Cleaved caspase-3/caspase-3 protein expression in PCOS rats after down-regulation of NEAT1 detected by Western blot analysis. E Bax/Bcl-2 protein expression in PCOS rats after down-regulation of NEAT1 detected by Western blot analysis; n = 8. The data are all measurement data, expressed as mean ± standard deviation, *P < 0.05 vs. the normal group; #P < 0.05 vs. the sh-NC group, and one-way ANOVA and Tukey’s post hoc test were used for statistical analysis

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Journal of Biomedical Science

ISSN: 1423-0127