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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: RETRACTED ARTICLE: Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis

Fig. 6

NEAT1 and IGF1 expression is elevated, and miR-381 expression is repressed in ovarian granulosa cells from PCOS rats. A NEAT1 expression in ovarian granulosa cells from PCOS rats after transfection by RT-qPCR; B miR-381 expression in ovarian granulosa cells from PCOS rats after transfection by RT-qPCR; C IGF1 mRNA expression in ovarian granulosa cells from PCOS rats after transfection by RT-qPCR; D IGF1 protein bands in ovarian granulosa cells from PCOS rats after transfection by Western blot analysis; E IGF1 protein expression in ovarian granulosa cells from PCOS rats after transfection by Western blot analysis N = 3. The data are all measurement data, expressed as mean ± standard deviation, *P < 0.05 vs. the sh-NC group; ^P < 0.05 vs. the pc-NC group; #P < 0.05 vs. the mimic NC group, &P < 0.05 vs. the pc-NEAT1 + mimic NC group, and one-way ANOVA and Tukey’s post hoc test were used for statistical analysis

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