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Fig. 7 | Journal of Biomedical Science

Fig. 7

From: RETRACTED ARTICLE: Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis

Fig. 7

Cell proliferation is promoted by silenced NEAT1 or elevated miR-381 in ovarian granulosa cells from PCOS rats. A Difference in cell viability after transfection of ovarian granulosa cells from PCOS rats by CCK-8 assay; B PCNA and cyclin D1 mRNA expression in ovarian granulosa cells from PCOS rats by RT-qPCR; C, D Colony formation ability of ovarian granulosa cells from PCOS rats detected by colony formation assay; N = 3. The data are all measurement data, expressed as mean ± standard deviation, *P < 0.05 vs. the sh-NC group; #P < 0.05 vs. the mimic NC group, &P < 0.05 vs. the pc-NEAT1 + mimic NC group, and one-way ANOVA and Tukey’s post hoc test were used for statistical analysis

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