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Fig. 8 | Journal of Biomedical Science

Fig. 8

From: RETRACTED ARTICLE: Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis

Fig. 8

Cell apoptosis is inhibited by silenced NEAT1 or elevated miR-381 in ovarian granulosa cells from PCOS rats. A Apoptosis of ovarian granulosa cells from PCOS rats after transfection by flow cytometry; B Comparison of apoptosis rate of ovarian granulosa cells from PCOS rats after transfection; C Caspase-3 mRNA expression in ovarian granulosa cells from PCOS rats after transfection; D Bax mRNA expression in ovarian granulosa cells after transfection; E Bcl-2 mRNA expression in ovarian granulosa cells from PCOS rats after transfection; N = 3. The data are all measurement data, expressed as mean ± standard deviation, *P < 0.05 vs. the sh-NC group; #P < 0.05 vs. the mimic NC group, &P < 0.05 vs. the pc-NEAT1 + mimic NC group, and one-way ANOVA and Tukey’s post hoc test were used for statistical analysis

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Journal of Biomedical Science

ISSN: 1423-0127