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Table 3 Mean ± standard deviation of multiparametric magnetic resonance imaging (mp-MRI) parameters for discrimination of cancer and normal tissue in the central gland

From: Diagnosis of transition zone prostate cancer by multiparametric MRI: added value of MR spectroscopic imaging with sLASER volume selection

Parameters Normal Cancer (low-risk, intermediate-risk and high-risk) p-value
ADC (10–6 mm2/s) 1112.42 ± 138.83 871.10 ± 149.61  < 0.01
Ktrans (min−1) 0.14 ± 0.08 0.24 ± 0.10  < 0.01
Kep (min−1) 0.65 ± 0.38 1.12 ± 0.53  < 0.01
iAUGC (mmol.min/L) 2.61 ± 1.04 3.15 ± 1.31  < 0.05
(Cho + Spm + Cr)/Cit 0.23 ± 0.09 1.60 ± 1.12  < 0.01
Cho/Cit 0.16 ± 0.08 0.82 ± 0.38  < 0.01
Cho/Cr 1.28 ± 0.68 2.94 ± 0.87  < 0.01
  1. ADC apparent diffusion coefficient, Ktrans the volume transfer constant, Kep the rate constant , iAUGC the area under gadolinium curve, Cho choline, Spm spermine, Cr creatine, Cit citrate