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Table 4 Area under receiver operating characteristic curve (AUC) and diagnostic accuracy, sensitivity and specificity of detecting central cancers by T2WI (standardized T2WI signal intensity), DWI (ADC), DCE (Ktrans, Kep and iAUGC) and MRSI ((Cho + Spm + Cr)/Cit, Cho/Cit and Cho/Cr)

From: Diagnosis of transition zone prostate cancer by multiparametric MRI: added value of MR spectroscopic imaging with sLASER volume selection

Model AUC (%95 CI) Accuracy Sensitivity Specificity
T2WI + DWI 0.86 (0.75–1.00) 0.83 (111/134) 0.80 (49/61) 0.85 (62/73)
T2WI + DWI + DCE 0.83 (0.70–1.00) 0.80 (107/134) 0.84 (51/61) 0.77 (56/73)
T2WI + DWI + MRSI 0.99 (0.97–1.00) 0.96 (129/134) 0.95 (58/61) 0.97 (71/73)
T2WI + DWI + DCE + MRSI 0.98 (0.95–1.00) 0.95 (127/134) 0.95 (58/61) 0.94 (69/73)
  1. T2WI T2-weighted imaging, DWI diffusion weighted imaging, DCE dynamic contrast enhancement, MRSI magnetic resonance spectroscopic imaging, CI confidence intervals