Fig. 7

β-catenin bonded ABCB1 promoter and activated ABCB1 transcription. A ChIP with β-catenin antibody in Hep3B-SR and HepG2-SR cells and the resulting precipitated DNA samples were quantified by qRT-PCR with ABCB1, ABCG2, LRP and MRP2 primers. B and C Dual luciferase reporter assay was used to detect the reporter activity after ten or twelve groups’ co-transfected as shown in Hep3B and HepG2 cells