Scheme 2
From: Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent

Synthetic route to methyl ether analogues 25 and 26. Reagents and conditions (a) K2CO3, BnBr, DMF; (b) NaH, MeI, THF; (c) Pd/C, H2, THF
From: Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent
Synthetic route to methyl ether analogues 25 and 26. Reagents and conditions (a) K2CO3, BnBr, DMF; (b) NaH, MeI, THF; (c) Pd/C, H2, THF