Scheme 3From: Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agentSynthetic route to analogues 28–30. Reagents and conditions (a) K2CO3, BnBr, DMF; (b) t-BuOK, MTPPB, THF; (c) NaH, dipropyl sulfate (39a) or allyl bromide (39b), DMF; (d) conc. HCl, MeOHBack to article page