Fig. 5
From: HBx facilitates ferroptosis in acute liver failure via EZH2 mediated SLC7A11 suppression
Fer-1 protects against LPS/D-GalN-induced ALF in mice. A The survival curve of sham, sham + Fer-1, LPS/D-GalN and LPS/D-GalN + Fer-1 mice. The serum levels of B ALT and C AST were assessed. D The histopathological changes were determined by H&E staining. The levels of E MDA, F GSH, G iron, H ROS and I TNFα, IL-6, IL-1β levels were assessed. *, P < 0.05, **, P < 0.01, ***, P < 0.001