Fig. 4

Protein expression levels of MCT1 and SMCT1 are downregulated in the spinal cord of ALS (G93A) mice. a, b SLC16A1 immunoreactivity was significantly decreased in motor neurons of the spinal cord of mutant SOD1 (G93A) ALS mice (n = 5) compared to WT mice (n = 5). c, d SLC5A8 immunoreactivity was significantly decreased in motor neurons of the spinal cord of mutant SOD1 (G93A) ALS mice (n = 5) compared to WT mice (n = 5). Cell counting, n = 50 (10 cells/case), **p < 0.001 significant difference from the WT mice