Fig. 5From: Monocarboxylate transporter functions and neuroprotective effects of valproic acid in experimental models of amyotrophic lateral sclerosisApoptotic pathway protein expression levels are changed in the spinal cord of ALS (G93A) mice. a, b BAX immunoreactivity was significantly increased in motor neurons of the spinal cord of mutant SOD1 (G93A) ALS mice (n = 5) compared to WT mice (n = 5). A total of 50 motor neurons were counted [10 motor neurons × 5 section (section/case)]. c, d BCL2 immunoreactivity was significantly decreased in motor neurons of the spinal cord of mutant SOD1 (G93A) ALS mice (n = 5) compared to WT mice (n = 5). A total of 50 motor neurons were counted [10 motor neurons × 5 section (section/case)]. **p < 0.001 significant difference from the WT mice. Scale bars: left, 100 μm; middle, 50 μm, right (inlet) 10 μmBack to article page