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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Monocarboxylate transporter functions and neuroprotective effects of valproic acid in experimental models of amyotrophic lateral sclerosis

Fig. 5

Apoptotic pathway protein expression levels are changed in the spinal cord of ALS (G93A) mice. a, b BAX immunoreactivity was significantly increased in motor neurons of the spinal cord of mutant SOD1 (G93A) ALS mice (n = 5) compared to WT mice (n = 5). A total of 50 motor neurons were counted [10 motor neurons × 5 section (section/case)]. c, d BCL2 immunoreactivity was significantly decreased in motor neurons of the spinal cord of mutant SOD1 (G93A) ALS mice (n = 5) compared to WT mice (n = 5). A total of 50 motor neurons were counted [10 motor neurons × 5 section (section/case)]. **p < 0.001 significant difference from the WT mice. Scale bars: left, 100 μm; middle, 50 μm, right (inlet) 10 μm

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