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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression

Fig. 1

The Sp1 level is decreased in women with lung cancer and associated with a poor prognosis. The survival rates in the early- (stage I and II) and late-stage (stage III and IV) cohorts were analyzed by Kaplan–Meier survival curves and HR assay (A). The level of Sp1 in 331 lung cancer patients was studied by IHC, and then the samples were grouped into Sp1-Low and Sp1-High groups (B). The relevance between survival rate and Sp1 level in total patients (C, upper panel), male patients (C, middle panel) and female patients (C, lower panel) was analyzed by Kaplan–Meier survival curves and HR assay

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