Skip to main content
Fig. 3 | Journal of Biomedical Science

Fig. 3

From: SLCO4A1-AS1 promotes colorectal tumourigenesis by regulating Cdk2/c-Myc signalling

Fig. 3

SLCO4A1-AS1 promotes CRC proliferation in vitro and in vivo. a Validation of SLCO4A1-AS1 expression in CRC cells transfected with SLCO4A1-AS1 overexpression (oeSLC) or shRNA (shSLC) plasmids. b The effects of SLCO4A1-AS1 on CRC cell proliferation were assessed by CCK-8 assays. c Effects of SLCO4A1-AS1 on the colony formation abilities of CRC cells. d The effects of SLCO4A1-AS1 on the cell cycle in CRC cells were evaluated by FACS. e The effect of SLCO4A1-AS1 on CRC tumour formation in a nude mouse xenograft model. Representative images of tumours from the SLCO4A1-AS1 (shSLC and oeSLC) and control groups (n = 7 for each group). *P < 0.05; **P < 0.01; ***P < 0.001

Back to article page