Fig. 2From: Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interferenceEffects of docetaxel, CAPE, and combination treatment on the survival of docetaxel-resistant PC/DX25 and DU/DX50 cells. The cell survival was determined by MTT assay. PC/DX25 cells were treated with increasing concentration (25, 50, 100, 200, 250, 375 nM) of docetaxel (A), increasing concentration (0, 10, 20, 40 μM) of CAPE (B), or combination of docetaxel plus 20 μM CAPE (C) for 96 h. DU/DX50 cells were treated with increasing concentration (50, 100, 200, 250, 375 nM) of docetaxel (D), increasing concentration (0, 10, 20, 40 μM) of CAPE (E), or combination of docetaxel plus 20 μM CAPE (F) for 96 h. Results were presented as mean ± standard error. Experiments were repeated for at least three times. The asterisks ** and *** represent p value < 0.01 and p value < 0.001, respectivelyBack to article page