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Fig. 8 | Journal of Biomedical Science

Fig. 8

From: Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interference

Fig. 8

Combination treatment affected the expression of proteins regulating cell proliferation, apoptosis, and agiogenesis in PC/DX25 xenografts. A Protein expression level of Ki67, Bcl-2, Bax, cleaved caspase-3, and CD31 in prostate tissues of control group mice (docetaxel treatment plus control vehicle) or combination treatment group mice (docetaxel treatment plus CAPE) carrying PC/DX25 xenografts was examined by immunohistochemistry staining. The magnification for images is 400X. Relative protein expression intensity was shown under each IHC image. B The relative protein expression intensity for Ki67, Bcl-2, Bax, cleaved caspase-3, and CD31 in prostate tissues of control group mice vs. combination treatment group mice was shown as heatmap using log2 value

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Journal of Biomedical Science

ISSN: 1423-0127