Fig. 9From: Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interferenceOverexpression of Bcl-2 increased cell proliferation of DU/DX50 cells under combination treatment. A A representative image of two clones of DU/DX50 cells transiently overexpressing Bcl-2 being confirmed by Western blotting. B Proliferation of control DU/DX50 and DU/DX50 cells overexpressing Bcl-2 being treated with 50 nM docetaxel plus increasing concentration of CAPE (0, 10, 20, 40 μM) for 96 h was examined by proliferation assay. Results were presented as mean ± standard error. Experiments were repeated for at least three times. The asterisks * and *** represent p value < 0.05 and p value < 0.0001, respectivelyBack to article page