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Table 1 Centriolar/centrosomal genes expression (microarray)

From: A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis

Gene

Lung cancer patients

Tumor (n = 163)

Paired non-malignant (n = 163)

Ratio (T/N)

p-value

STIL/MCPH7

137.8

39.5

3.5

1.8E−29

SASS6

122.5

75.3

1.6

1.0E−19

SPICE1

184.1

116.7

1.5

1.1E−18

PLK4

57.8

37.7

1.5

2.3E−22

CEP295/KIAA1731

73.1

53.5

1.3

5.7E−08

POC5

212.4

164.4

1.2

3.6E−08

CEP152/MCPH9

27.4

24.1

1.1

8.1E−08

CPAP/CENPJ/MCPH6

111.7

104.6

1.0

4.3E−03

CETN1

27.3

26.6

1.0

8.8E−02

RTTN

141.7

139.4

1.0

1.9E−03

CEP135/MCPH8

81.7

81.6

1.0

5.6E−02

CEP63

128.9

144.0

0.9

1.3E−01

POC1B

376.0

425.2

0.9

3.8E−03

CEP120

401.9

507.8

0.8

3.1E−11

  1. The microarray data of 163 paired lung cancer patients and their adjacent non-malignant lung tissues were derived from GEO
  2. Ranking is based on the ratio between tumor (T) and paired non-malignant lung specimens (N)
  3. Significance is determined by paired t-test