Skip to main content
Fig. 2 | Journal of Biomedical Science

Fig. 2

From: The effects of SARS-CoV-2 infection on modulating innate immunity and strategies of combating inflammatory response for COVID-19 therapy

Fig. 2

The activation and effect of NLRP3 [36, 37]. The activation of NLRP3 can be realized through directly binding to the receptor, or through RAAS, and ComC. Subsequently, NLRP3 assemble and active caspase-1 further allow IL-1β and IL-18 to release. ACE2, angiotensin converting enzyme; RAAS, renin–angiotensin–aldosterone system; ComC, complement cascade; GSDMD, gasdermin D. (Created with BioRender.com.)

Back to article page

Journal of Biomedical Science

ISSN: 1423-0127