Fig. 10From: Inhibition of ChREBP ubiquitination via the ROS/Akt-dependent downregulation of Smurf2 contributes to lysophosphatidic acid-induced fibrosis in renal mesangial cellsSchematic representation of the mechanism by which LPA induces ChREBP-mediated fibrosis, via the ROS/Akt-dependent downregulation of Smurf2 in renal mesangial cells. Created with BioRender.com. Red and blue arrows indicate upregulated and downregulated responses, respectivelyBack to article page