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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway

Fig. 6

KRT17 silencing potentiates therapeutic efficacies of cisplatin, carboplatin and dasatinib in OSCC. A Dose-dependent cell viability assays were performed to examine the effect of KRT17 silencing on drug sensitivity of C9IV3 and HSC3 cells that were treated with cisplatin or carboplatin ranging from 0 to 100 μM. B Dose-dependent cell viability assays were performed to investigate whether combinatorial treatments of dasatinib with cisplatin or carboplatin could be therapeutically more effective against C9IV3 and HSC3 cells. Data are presented as the mean ± SD (*p < 0.05, **p < 0.01 and ***p < 0.001)

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