Cancer type | Title of the trial | State | Number of participants | ClinicalTrials.gov Identifier |
---|---|---|---|---|
Thyroid cancer | Anaplastic thyroid cancer and follicular thyroid cancer-derived exosomal analysis via treatment of lovastatin and vildagliptin and pilot prognostic study via urine exosomal biological markers in thyroid cancer patients | Completed | 22 | NCT02862470 [182] |
Lung cancer | Serum exosomal long noncoding RNAs as potential biomarkers for lung cancer diagnosis | Completed | 1000 | NCT03830619 |
Pancreatic cancer | Diagnostic accuracy of circulating tumor cells (CTCs) and onco-exosome quantification in the diagnosis of pancreatic cancer—PANC-CTC | Completed | 52 | NCT03032913 |
Acquisition of portal venous circulating tumor cells and exosomes from patients with pancreatic cancer by endoscopic ultrasound: a prospective study | Ongoing | Estimated 30 | NCT03821909 | |
Prostate cancer | Clinical validation of a urinary exosome gene signature in men presenting for suspicion of prostate cancer | Completed | 2000 | NCT02702856 [183] |
Clinical evaluation of ExoDx™ prostate (IntelliScore) in men presenting for initial prostate biopsy | Completed | 120 | NCT04720599 | |
Rectal cancer | Exosomal as correlative biomarker in clinical outcomes in patients undergoing neoadjuvant chemoradiation therapy for rectal cancer | Ongoing | Estimated 30 | NCT03874559 |
A prospective, observational, multicenter study on biomarkers for predicting the efficacy and toxicities of neoadjuvant chemoradiotherapy for locally advanced rectal cancer based on tissue and plasma exosome RNA | Ongoing | Estimated 250 | NCT04227886 | |
Gastric cancer | Circulating exosomes as potential prognostic and predictive biomarkers in advanced gastric cancer patients: a prospective observational study (“EXO-PPP Study”) | Ongoing | Estimated 80 | NCT01779583 |
Ovarian cancer | Non-coding RNA in the exosome of the epithelia ovarian cancer | Ongoing | Estimated 160 | NCT03738319 |
Bladder cancer | A study of circulating exosome proteomics in gallbladder carcinoma patients | Ongoing | Estimated 50 | NCT03581435 |
Cholangiocarcinoma | Exosomes-derived ncRNAs as biomarkers in cholangiocarcinoma patients | Ongoing | Estimated 80 | NCT03102268 |