Fig. 3
From: Homozygous mutation of the LRRK2 ROC domain as a novel genetic model of parkinsonism
Several parameters of measured by the CatWalk system were affected in various ways in four mice. The swing velocity, cadence, and stride length were decreased in hLRRK2 R1441G HOM mice. In contrast, the stance duration and the pressure on the hind-paws BOS increased in hLRRK2 R1441G HOM mice. Data are presented as the mean ± SD (n = 5). *Significant effect, p < 0.05; **significant effect, p < 0.01; ***significant effect, p < 0.005; ****significant effect, p < 0.001